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折扣/货期| 货号：GTX03003-02 | 规格：250μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TGF beta 1 antibody [MT517] (Biotin)
别名:
CED,DPD1,LAP,TGFB,TGFB1,TGFbeta,transforming growth factor beta 1,TGF beta 1
反应种属:
Human, Monkey
宿主来源:
Mouse
实验应用:
ELISA, Sandwich ELISA
靶标/特异性:
This antibody is able to detect native and recombinant human latent Transforming Growth Factor-帣1 (TGF-帣1), binds to the Latency Associated Protein (LAP), which is a part of the latent TGF-帣1 complex and does not bind to latent TGF-帣2 or -帣3.
同种型:
IgG1
免疫原:
Recombinant latent TGF-β1
克隆性:
Monoclonal
克隆号:
MT517
纯化方式:
Protein G purified
偶联:
Biotin
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
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