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折扣/货期| 货号：47-130 | 规格：200 ug | 目录价：￥9126 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Thymidine Kinase Antibody [3B3.E11]
别名:
DNA ligase 1, DNA ligase I,
反应种属:
Human
宿主来源:
Mouse
同种型:
IgG1
克隆性:
Monoclonal
克隆号:
3B3.E11
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
This antibody is stable for at least one (1) year at -20˚C. Avoid multiple freeze- thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS
产地:
美国
生产商:
Prosci
功能与背景:
Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. High levels of these enzymes are present in proliferating cells, and low levels are found in resting cells, due to multiple regulatory mechanisms that ensure exclusive expression of these enzymes in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.
Accession #:
P18858
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