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折扣/货期| 货号：47-129 | 规格：200 ug | 目录价：￥9126 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Thymidylate Synthase Antibody [2D8.D11]
别名:
RAD51A, RECA, DNA repair protein RAD51 homolog 1, RAD51 homolog A, HsRAD51, BRCC5, MRMV2, HRAD51, HsRad51, HsT16930
反应种属:
Human
宿主来源:
Mouse
同种型:
IgG1
克隆性:
Monoclonal
克隆号:
2D8.D11
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
This antibody is stable for at least one (1) year at -20˚C. Avoid multiple freeze- thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS
产地:
美国
生产商:
Prosci
功能与背景:
Thymidylate synthase (TS) is anintracellular enzyme critical for de novosynthesis of DNA. In cancer,expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
Accession #:
NP_001157741.1
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