| 货号:GTX17898 | 规格:250μl | 目录价:¥6600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Thyroid Hormone Receptor beta antibody [SPM222]
别名:
thyroid hormone receptor beta , C-ERBA-2 , C-ERBA-BETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB1 , THRB2
反应种属:
Dog, Human
宿主来源:
Mouse
实验应用:
IHC-P
靶标/特异性:
Recognises human thyroid receptor beta, does not recognise alpha 1 and alpha 2 isotypes.
同种型:
IgG1
免疫原:
Synthetic peptide: GMSEACLHRKSHSERRSTLK, corresponding to N terminal amino acids 31-50 of Human Thyroid Hormone Receptor beta.
克隆性:
Monoclonal
克隆号:
SPM222
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, BSA, Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
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