官网链接
折扣/货期| 货号：GTX86914 | 规格：100μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Thyroid Hormone Receptor beta (cleaved Arg327) antibody
别名:
CERBA2 , CERBABETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB , THRB1 , THRB2 , thyroid hormone receptor beta , Thyroid Hormone Receptor beta , thyroid hormone receptor, beta
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
Thyroid Hormone Receptor beta (cleaved Arg327) antibody detects endogenous levels of fragment of activated THRB resulting from cleavage adjacent to Arg327.
同种型:
IgG
免疫原:
The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor beta (278-327).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
53
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
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