TIM-3 Detection Set (Risk Free)-其他-深圳欣博盛生物科技有限公司

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TIM-3 Detection Set (Risk Free)

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：RF16100

规格：1 Set

目录价：￥7590.375

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TIM-3 Detection Set (Risk Free)

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA,WB,ICC,IHC-P,Flow,IF

同种型:

IgG1, IgG2b

克隆性:

Monoclonal

纯化方式:

Antibodies are supplied as protein A purified IgG1.

偶联:

Unconjugated

产品浓度:

Antibody 1 mg/mL

保存温度:

Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

The immune checkpoint protein TIM3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-γ producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells. It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses, and is also highly expressed on regulatory T cells, monocytes, macrophages, and dendritic cells (1). TIM3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice; blocking TIM3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3). ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

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