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折扣/货期| 货号：GTX21655 | 规格：100μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TLR2 antibody
别名:
CD282,TIL4,TLR2,toll like receptor 2
反应种属:
Human, Mouse
宿主来源:
Goat
实验应用:
ELISA, IHC
靶标/特异性:
Peptide sequence is < 50 % identical to other human TLR receptors in this region.
同种型:
IgG
免疫原:
Synthetic peptide C-LEIDASDLQSYEPKSLKSIQNVSHLI corresponding to amino acids 179-204 of human TLR2
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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