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折扣/货期| 货号：GTX638477-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX638477 | 规格：100μl | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TLR3 antibody [HL2314]
别名:
toll like receptor 3 , CD283 , IIAE2
反应种属:
Cat, Dog, Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P, WB
靶标/特异性:
The immunogen sequence of this antibody is within cleaved form TLR3 protein, so this antibody is expected to detect both full-length and cleaved form TLR3 protein.
同种型:
IgG
免疫原:
Recombinant fragment of human TLR3.
克隆性:
Monoclonal
克隆号:
HL2314
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]
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