深圳欣博盛生物科技有限公司 a1

货号:GTX45944 规格:50μg 目录价:¥6000
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TMEM16C antibody, Internal
别名:
anoctamin 3 , C11orf25 , DYT23 , DYT24 , GENX-3947 , TMEM16C
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
A synthetic peptide corresponding to an Internal region of Human TMEM16C
克隆性:
Polyclonal
克隆号:
纯化方式:
Affinity Purified
偶联:
Unconjugated
产品浓度:
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
115
产品形式:
Liquid
存储溶液:
PBS, 2% Sucrose, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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