TMEM2 antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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TMEM2 antibody, Internal

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX47035

规格：50μg

目录价：￥6100

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TMEM2 antibody, Internal

别名:

cell migration inducing hyaluronidase 2 , TMEM2

反应种属:

Human

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

A synthetic peptide corresponding to an Internal region of Human TMEM2

克隆性:

Polyclonal

克隆号:

纯化方式:

Affinity Purified

偶联:

Unconjugated

产品浓度:

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

154

产品形式:

Liquid

存储溶液:

PBS, 2% Sucrose, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]

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