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折扣/货期| 货号：GTX00577-08 | 规格：100test | 目录价：￥4800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TNF Receptor I antibody [H398] (PE)
别名:
CD120a , FPF , TBP1 , TNF receptor superfamily member 1A , TNFAR , TNFR , TNFR1 , TNFR55 , TNFR60 , TNFRI , TNFRSF1A , p55 , p55R , p60 , TNF receptor I , TNF-R1 , TNF-RI
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM
靶标/特异性:
This antibody recognizes the extracellular domain of CD120a. The antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.
同种型:
IgG2a
免疫原:
Recombinant full length human CD120a
克隆性:
Monoclonal
克隆号:
H398
纯化方式:
Purified by size-exclusion chromatography
偶联:
PE
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]
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