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折扣/货期| 货号：GTX54416 | 规格：50μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TNF Receptor I antibody [MR1-2]
别名:
CD120a,FPF,TBP1,TNF receptor superfamily member 1A,TNFAR,TNFR,TNFR1,TNFR55,TNFR60,TNFRI,TNFRSF1A,p55,p55R,p60,TNF receptor I,TNF-R1,TNF-RI
反应种属:
Cynomolgus monkey, Human, Rhesus Monkey
宿主来源:
Mouse
实验应用:
FCM, Functional Assay
靶标/特异性:
The antibody MR1-2 reacts with the extra-cellular part of the TNF-RI. It also reacts with the soluble receptor.
同种型:
IgG1
免疫原:
Extracellular part of TNF-R55
克隆性:
Monoclonal
克隆号:
MR1-2
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
100 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, 0.1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]
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