TREM2 (mouse) blocking peptide-封闭肽-深圳欣博盛生物科技有限公司

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TREM2 (mouse) blocking peptide

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX47596-PEP

规格：100μg

目录价：￥3200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TREM2 (mouse) blocking peptide

别名:

Triggering Receptor Expressed On Myeloid Cells 2 , Trem-2 , Trem2A , Trem2B , Trem2C , Trem2

靶标/特异性:

The peptide was used in the production of GTX47596.

克隆号:

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is part of the immunoglobulin and lectin-like superfamily and functions as part of the innate immune system. This gene forms part of a cluster of genes on mouse chromosome 17 thought to be involved in innate immunity. This protein associates with the adaptor protein Dap-12 and recruits several factors, such as kinases and phospholipase C-gamma, to form a receptor signaling complex that activates myeloid cells, including dendritic cells and microglia. In humans homozygous loss-of-function mutations in this gene cause Nasu-Hakola disease and mutations in this gene may be risk factors to the development of Alzheimer's disease. In mouse mutations of this gene serve as a pathophysiological model for polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu-Hakola disease) and for inflammatory bowel disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 20

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