TRIM30 antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

TRIM30 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85386

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TRIM30 antibody

别名:

tripartite motif-containing 30A , Rpt-1 , Rpt1 , Trim30

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

This antibody is specific for TRIM30 C-Terminus

同种型:

IgG

免疫原:

TRIM30 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the mouse TRIM30.The immunogen is located within amino acids 250 - 300 of TRIM30.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity; TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NFkappa-B activation. The importance of TRIM30 in the attenuation or termination of NFkappa-B activation suggests that targeting of TAB2 and TAB3 by TRIM30 alpha may be a mechanism for modulating many types of immune responses.

您可能感兴趣的产品

Anti-Cathepsin D

货号：01-12-030104-1mg

Tafazzin Polyclonal Antibody

SARS-CoV-2 (COVID-19) nsp3 antibody

货号：GTX135589-S

SARS-CoV-2 (COVID-19) nsp12 antibody