TrkB antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

TrkB antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX10841

规格：25μg

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TrkB antibody

别名:

neurotrophic receptor tyrosine kinase 2 , EIEE58 , GP145-TrkB , OBHD , TRKB , trk-B

反应种属:

Human

宿主来源:

Goat

实验应用:

同种型:

IgG

免疫原:

recombinant human TrkB extracellular domain expressed in NS0 cells.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 5% Trehalose, no preservatives.

生产商:

GeneTex

功能与背景:

Neurotrophins activate tyrosine kinase receptors of the trk family (trkA, trkB and trkC) and they all share a common low affinity receptor (p75^NTR or p75). Although p75^NTR does not appear to directly transduce NGF signals, this receptor appears to increase the responsiveness of the trk receptors and plays a role in the retrograde transport of neurotrophin signals from axon terminals to the cell body. The expression of trk gene neurotrophin receptors in mouse is tabulated by Barbacid (1994). NGF binds with high affinity and activates the TrkA tyrosine kinase receptor, which is apparently responsible for signal transduction. BDNF activates the TrkB tyrosine kinase receptor, which it shares with NT-4. NT-3 activates the TrkC tyrosine kinase receptor, but can also activate TrkA and TrkB receptors in certain cell systems. NT-4 primarily activates the TrkB tyrosine kinase receptor, which it shares with BDNF.

您可能感兴趣的产品

Lyve-1 (human) antibody

货号：RLT-102-PABI50

Anti-Collagenase (Clostridium histolyticum), polyclonal antibody from sheep

货号：NB-58050-01

Anti-Collagenase (Clostridium histolyticum) HRP, polyclonal antibody from sheep