TrxR1 antibody, C-term-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

TrxR1 antibody, C-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX13574

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TrxR1 antibody, C-term

别名:

thioredoxin reductase 1 , GRIM-12 , TR , TR1 , TRXR1 , TXNR

反应种属:

Human

宿主来源:

Goat

实验应用:

IHC-P, WB

靶标/特异性:

This antibody is expected to recognise reported isoform 1 (NP_003321.2), isoform 2 (NP_877393.1; NP_877419.1; NP_877420.1) and isoform 3 (NP_001087240.1)

同种型:

IgG

免疫原:

Peptide with sequence TKRSGASILQAGC, from the C Terminus of the protein sequence according to NP_003321.2; NP_877393.1; NP_877419.1; NP_877420.1; NP_001087240.1.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

偶联:

Unconjugated

产品浓度:

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

TBS, 0.5% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms, including a glutaredoxin-containing isoform that is predominantly expressed in testis. [provided by RefSeq, May 2017]

您可能感兴趣的产品

Lyve-1 (human) antibody

货号：RLT-102-PABI50

Anti-Collagenase (Clostridium histolyticum), polyclonal antibody from sheep

货号：NB-58050-01

Anti-Collagenase (Clostridium histolyticum) HRP, polyclonal antibody from sheep