货号:SBB-CE0027-C100 | 规格:100 ug | 目录价:¥4032 |
产品详情
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产品名称:
UBE2D2 [UbcH5b] (human) (rec.) (untagged)
别名:
Ubiquitin-conjugating Enzyme H5b; PUBC1; UBC5B; Ubiquitin-protein Ligase D2; p53-regulated Ubiquitin-conjugating Enzyme 1
产品描述:
UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D2-Ub thioester. UBE2D2 is capable of associating with numerous known E3 ligases which target abnormal proteins for proteasomal degradation through polyubiquitination. UBE2D2 is also known to interact with Parkin and to be involved in PINK1 mediated mitophagy.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~17kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol (v/v), 2mM TCEP.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
促销活动
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