| 货号:GTX114131 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX114131-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
UGT1A antibody
别名:
BILIQTL1 antibody , GNT1 antibody , HUG-BR1 antibody , UDPGT antibody , UDPGT 1-1 antibody , UGT1 antibody , UGT1A antibody , UGT1A1 antibody , UDP-glucuronosyltransferase 1A1 antibody , UDP glycosyltransferase 1 family , polypeptide A1 antibody , bilirubin-specific UDPGT isozyme 1 antibody , UGT1.1 antibody , UDP-glucuronosyltransferase 1-1 antibody , UGT-1A antibody , bilirubin UDP-glucuronosyltransferase isozyme 1 antibody , UGT1*1 antibody , bilirubin UDP-glucuronosyltransferase 1-1 antibody , UDP-glucuronosyltransferase 1-A antibody , UGT1-01 antibody , UDP glucuronosyltransferase 1 family , polypeptide A1 antibody
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human UGT1A. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.93 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
60
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq]
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