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折扣/货期| 货号：SIH-610-5MG | 规格：5 mg | 目录价：￥1252.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Urolithin A
别名:
3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one; or 2',7-Dihydroxy-3,4-benzocoumarin
产品描述:
Mitophagy inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
228.2
产品形式:
Pale-yellow powder
产地:
加拿大
功能与背景:
Urolithin A (UA) is a microbial metabolite of dietary ellagitannins produced in the gut (1). It has been shown to induce mitophagy and prolong lifespan in C. elegans and increase muscle function in rodents (2). It promotes mitophagy and suppresses NLRP3 inflammasome activation in LPS-induced BV2 microglial cells and in an MPTP-induced Parkinson’s disease model (3). The pro-mitophagy activity of Urolitin A may be beneficial in Alzheimer’s disease (4). Ex vivo UA-treated T cells display improved anti-tumor function (5).
纯度:
>98% (HPLC); NMR (Conforms)
来源:
Synthetic
CAS号:
1143-70-0
分子式:
C13H8O4
溶解度:
May be dissolved in DMSO (50 mg/ml)
PubChem CID:
5488186
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