VEGF-D Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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VEGF-D Recombinant Protein

品牌：ProSci LLC

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说明书

折扣/货期

货号：40-166-0.002 mg	规格：0.002 mg	目录价：￥3783
货号：40-166-0.01 mg	规格：0.01 mg	目录价：￥5674.5

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

VEGF-D Recombinant Protein

别名:

VEGFD, VEGF-D, VEGFD, Vascular endothelial growth factor D, c-Fos-induced growth factor

表达系统:

HEK293 cells

保存温度:

The lyophilized VEGF-D recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted VEGF-D is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing VEGF-D recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Blue Ice

产品形式:

Lyophilized

产地:

美国

生产商:

Prosci

功能与背景:

VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant human VEGF-D is a 13.1 kDa non-disulfide linked homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

生物活性:

Measured by its ability to bind recombinant human VEGFR3/Flt-4 Fc in a functional ELISA.

Accession #:

NP_004460.1

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