Vitamin D Receptor (phospho Ser208) antibody-多抗-深圳欣博盛生物科技有限公司

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Vitamin D Receptor (phospho Ser208) antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX52380

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Vitamin D Receptor (phospho Ser208) antibody

别名:

NR1I1,PPP1R163,VDR,vitamin D (1,25 dihydroxyvitamin D3) receptor,Vitamin D Receptor,vitamin D receptor

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ICC/IF, WB

同种型:

IgG

免疫原:

The antiserum was produced against synthesized phosphopeptide derived from human Vitamin D Receptor around the phosphorylation site of serine 208 (D-L-Sp-E-E).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]

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