VRK1 antibody [1F6]-单抗-深圳欣博盛生物科技有限公司

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VRK1 antibody [1F6]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX79470

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

VRK1 antibody [1F6]

别名:

VRK serine/threonine kinase 1 , PCH1 , PCH1A

反应种属:

Human, Mouse

宿主来源:

Mouse

实验应用:

ICC/IF, IHC, IHC-P, WB

同种型:

IgG1

免疫原:

Recombinant fusion protein GST-VRK1.

克隆性:

Monoclonal

克隆号:

1F6

纯化方式:

Protein A purified

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.1% BSA, 0.05% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]

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