| 货号:GTX00703 | 规格:100μg | 目录价:¥5600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
VRK1 antibody [5D1]
别名:
VRK serine/threonine kinase 1 , PCH1 , PCH1A
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC, IP, WB
同种型:
IgG1
免疫原:
Synthetic peptide corresponding to N-terminus of human VRK1, MPRVKAAQAGRQSSAKRHL-C
克隆性:
Monoclonal
克隆号:
5D1
纯化方式:
Purified IgG
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
45
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, 50% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
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