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折扣/货期| 货号：GTX01958 | 规格：500μl | 目录价：￥9300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Wilms Tumor 1 antibody [WT49]
别名:
WT1 transcription factor , AWT1 , GUD , NPHS4 , WAGR , WIT-2 , WT33
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
IgG1
免疫原:
A prokaryotic recombinant protein containing 1–181 amino acids of the N-terminal of the Wilms’ Tumor protein.
克隆性:
Monoclonal
克隆号:
WT49
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
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