官网链接
折扣/货期| 货号：AG-CR1-3694-M005 | 规格：5 mg | 目录价：￥360 |
| 货号：AG-CR1-3694-M025 | 规格：25 mg | 目录价：￥1140 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
WZB117
别名:
WZB-117; 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)
产品描述:
Glucose transporter GLUT inhibitor (GLUT4 > GLUT1 = GLUT3). Fast-acting irreversible GLUT1 inhibitor. Binds directly to GLUT1 involving three hydrogen bonds, one each with Asn34, Arg126 and Trp412. Blocks glucose transport in diverse cancer cells, reducing extracellular lactate and intracellular ATP levels and consequently decreases glycolysis. Anticancer agent in vitro and in vivo. Inhibits cancer cell proliferation, resulting in cell cycle arrest, senescence and necrosis or apoptosis. Inhibits the self-renewal and tumor-initiating capacity of cancer stem cells, blocking tumor initiation after implantation of cancer stem cells in mice.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
368.3
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
1223397-11-2
分子式:
C20H13FO6
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