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折扣/货期| 货号：GTX646470-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX646470 | 规格：100μl | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
xCT / SLC7A11 antibody [HL5661]
别名:
solute carrier family 7 member 11 , CCBR1 , xCT
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF
靶标/特异性:
This antibody was raised against human xCT / SLC7A11 Intracellular domain.
同种型:
IgG
免疫原:
Recombinant fragment encompassing a sequence within the Intracellular domain of human xCT / SLC7A11. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL5661
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
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