深圳欣博盛生物科技有限公司 a1

ZAP70 (phospho Tyr493) antibody
货号:GTX78921 规格:100μg 目录价:¥5300
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ZAP70 (phospho Tyr493) antibody
别名:
ADMIO2,IMD48,SRK,STCD,STD,TZK,ZAP70,zeta chain of T cell receptor associated protein kinase 70
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
IgG
免疫原:
The antiserum was produced against synthesized phosphopeptide derived from human Zap-70 around the phosphorylation site of tyrosine 493 (S-Y-Yp-T-A).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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