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折扣/货期| 货号：91-661 | 规格：0.05 mg | 目录价：￥11969.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
15-PGDH Recombinant Protein
别名:
15-Hydroxyprostaglandin Dehydrogenase [NAD(+)], 15-PGDH, Prostaglandin Dehydrogenase 1, HPGD, PGDH1
表达系统:
Human Cells
保存温度:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
Supplied as a 0.2 um filtered solution of 20mM HEPES,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
产地:
美国
生产商:
Prosci
功能与背景:
15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.
纯度:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Accession #:
P15428
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