3,4-Dimethoxychalcone-其他小分子化合物-深圳欣博盛生物科技有限公司

首页产品中心其他小分子化合物

3,4-Dimethoxychalcone

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0531-M010	规格：10 mg	目录价：￥360
货号：AG-CN2-0531-M050	规格：50 mg	目录价：￥660
货号：AG-CN2-0531-M250	规格：250 mg	目录价：￥1680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

3,4-Dimethoxychalcone

别名:

3,4-DMC; NSC643172; 3-(3,4-Dimethoxyphenyl)-1-phenylprop-2-en-1-one

产品描述:

Caloric restriction mimetic (CRM). Caloric restriction mimetics (CRMs) are natural or synthetic compounds that mimic the health-promoting and longevity-extending effects of caloric restriction. CRMs provoke the deacetylation of cellular proteins coupled to an increase in autophagic flux in the absence of toxicity. Induces the deacetylation of cytoplasmic proteins and stimulates autophagic flux, requiring transcription factor EB (TFEB)- and E3 (TFE3)-dependent gene transcription and mRNA translation to trigger autophagy. Stimulates the translocation of TFEB and TFE3 into nuclei both in vitro and in vivo, in hepatocytes and cardiomyocytes. Consequently induces autophagy in vitro and in vivo, mediates autophagy-dependent cardioprotective effects and improves the efficacy of anticancer chemotherapy in vivo. So far this chalcone polyphenol has been used as an intermediate for synthesis of biochemical substances and was described to have weak antioxidant and antimicrobial activity.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

268.3

产品形式:

solid

产地:

瑞士