| 货号:CDX-B0301-G001 | 规格:1 g | 目录价:¥826 |
| 货号:CDX-B0301-G005 | 规格:5 g | 目录价:¥3136 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
5-Bromo-2'-deoxyuridine
别名:
5-BrdU; 5-Bromo-1-(2-deoxy-beta-D-ribofuranosyl)uracil; 5-Bromouracil deoxyriboside; BUdR; Bromodeoxyuridine; Broxuridine; NSC 38297
产品描述:
The synthetic nucleoside 5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA and commonly used in the detection of proliferating cells in living tissues. It can be incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies with fluorescent tags to target the BrdU incorporation for detection via flow cytometry or fluorescence microscopy. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat. BrdU is also used as a mutagen in genetic research. BrdU stimulates cellular differentiation and maturation in leukemia cell lines, while it inhibits differentiation of friend erythroleukemia cells. BrdU replaces Oct-4 in transcription factor-mediated reprogramming of somatic cells and can be used in small molecule cocktail to generate ciPSCs.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
307.1
产品形式:
solid
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
59-14-3
分子式:
C9H11BrN2O5
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