6-Amino-DL-luciferin-其他小分子化合物-深圳欣博盛生物科技有限公司

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6-Amino-DL-luciferin

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-A0094-M001	规格：1 mg	目录价：￥1134
货号：CDX-A0094-M005	规格：5 mg	目录价：￥2282

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

6-Amino-DL-luciferin

别名:

4,5-Dihydro-2[6-amino-2-benzthiazolyl]-4-thiazole carboxylic acid

产品描述:

This is the racemic mixture containing both the D- and L-enantiomers of 6-amino-luciferin. While the D-enantiomer is active with firefly luciferase, the L-enantiome is less active. This amino analog of the common D-luciferin substrate is used in measuring firefly luciferase activity. The cell permeable reagent can be used when considering design of proluminescent bioconjugates (peptidase substrates) of luciferin for ultrasensitive luminescent assays. In bioluminescent protease assays peptides or amino acids are conjugated to the luciferin analog 6-amino-D-luciferin. These substrates are useful for ultrasensitive analysis of a variety of protease enzymes including various caspases and cathepsins, chymotrypsin, trypsin, elastase, kallikrein, thrombin, ficin, bromoalain, plasmin, papain, ficin and many others or even for use in vivo tracing of luciferase transfected cells in living tissues. The resulting bioluminescence spectrum of reaction of 6-Amino-D-luciferin is very similar to that observed for the natural substrate D-luciferin. Peptidase assays using a bioluminogenic substrate can be easily adapted to 96-well formats for HTS-based assays. Using this principle, it is possible to design an assay to detect almost any peptidase or protease activity via bioluminescence by using a substrate with a suitable peptide sequence. Applications in pathogen detection, discovery of protease inhibitors, probing cell physiology and assessing protease activity in oncogenesis are possible at extraordinary sensitivity.

宿主来源:

Synthetic

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

279.34

产品形式:

solid

产地:

瑞士