深圳欣博盛生物科技有限公司 a1

ACE-2 Recombinant Protein
品牌:ProSci LLC
货号:10-014 规格:0.1 mg 目录价:¥10126.35
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ACE-2 Recombinant Protein
别名:
Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
产品浓度:
batch dependent
表达系统:
HEK293 cells
保存温度:
Store in working aliquots at -20˚C. Avoid freeze/thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
20mM Tris, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4.
产地:
美国
生产商:
Prosci
功能与背景:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family which includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase and converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, heart, colon, small intestine and ovary at moderate levels. ACE2 is not inhibited by the classical ACE inhibitors, captopril and lisinopril and may play an important role in regulating the heart function.
纯度:
>95% as determined by reducing SDS-PAGE.
生物活性:
Human ACE2 protein can bind with SARS-CoV-2 Spike protein (RBD) in functional ELISA assay.
Accession #:
Q9BYF1
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