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折扣/货期| 货号：GTX52510 | 规格：50μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Activin Receptor Type IIB antibody [6L11]
别名:
ACTRIIB , ACVR2B , ActRIIB , HTX4 , activin A receptor type 2B , Activin Receptor Type IIB , Activin receptor 2B , Activin RIIB
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
靶标/特异性:
This antibody was selected for its ability to detect human Activin RIIB. Weak cross reactivity was found to Activin RIIA
同种型:
IgG1
免疫原:
Recombinant Activin RIIB extra cellular domain
克隆性:
Monoclonal
克隆号:
6L11
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
58
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
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