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折扣/货期| 货号：GTX52506 | 规格：50μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BMPR1B antibody [3E12]
别名:
ALK6 , AMDD , BDA1D , BDA2 , BMPR1B , CDw293 , bone morphogenetic protein receptor type 1B , BMPR-IB
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
靶标/特异性:
This antibody was selected for its ability to detect human BMPR1B. No cross reactivity was found to ALK3 (BMPR-IA)
同种型:
IgG2
免疫原:
Recombinant hu-ALK6 extra cellular domain
克隆性:
Monoclonal
克隆号:
3000000000000
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
57
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
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