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折扣/货期| 货号：40-614-0.005 mg | 规格：0.005 mg | 目录价：￥3783 |
| 货号：40-614-0.025 mg | 规格：0.025 mg | 目录价：￥5674.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Adiponectin Recombinant Protein
别名:
APN, Acdc, apM1, 30kDa, GBP28, adipo, Acrp30, Apm1, Adiponectin, 30 kDa adipocyte complement-related protein, ACRP30
表达系统:
High-5 Insect cells
保存温度:
The lyophilized Adiponectin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Adiponectin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Adiponectin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Adiponectin is an adipose-derived secreted protein containing 236 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-β and class A scavenger receptor in macrophages). Recombinant Murine Adiponectin is a multimeric glycoprotein, which has a calculated molecular weight of 25.8 kDa and contains amino acids Val-21 to Asn-247 of the adiponectin precursor protein fused to an N-terminal histidine tag. As a result of glycosylation, Recombinant Murine Adiponectin migrates with an apparent molecular mass of approximately 31-36 kDa by SDS-PAGE gel, under reducing conditions.
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by a cytotoxic assay using M1 cells. The ED50 for this effect is 4.0-6.0 μg/mL.
Accession #:
NP_033735.3
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