Afatinib-其他小分子化合物-深圳欣博盛生物科技有限公司

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Afatinib

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：SYN-1100-M001	规格：1 mg	目录价：￥1204
货号：SYN-1100-M005	规格：5 mg	目录价：￥1820
货号：SYN-1100-M010	规格：10 mg	目录价：￥3024
货号：SYN-1100-M050	规格：50 mg	目录价：￥8316
货号：SYN-1100-M100	规格：100 mg	目录价：￥询价

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Afatinib

别名:

Tovok; BIBW-2992

产品描述:

Afatinib is an irreversible kinase inhibitor and binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit tyrosine kinase autophosphorylation. This results in a downregulation of ErbB signaling and subsequent inhibition of proliferation of cell lines expressing wild-type EGFR, selected EGFR exon 19 deletion mutations, or exon 21 L858R mutations. It also inhibited in vitro proliferation of cell lines overexpressing HER2. Overall, tumor growth was inhibited by Afatinib very effectively with low nanomolar IC(50) values ranging from approximately 6nM to below 500nM.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

486

产品形式:

solid

产地:

瑞士

纯度:

>95%