AKT1 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

首页产品中心其他重组蛋白

AKT1 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-020

规格：0.025 mg

目录价：￥10986.3

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

AKT1 Recombinant Protein

别名:

AKT1, PKB, RAC, RAC-PK-alpha, PKB alpha

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

20 mM tris, 150 mM NaCl, pH8.0

产地:

美国

生产商:

Prosci

功能与背景:

RAC-alpha serine/threonine-protein kinase (AKT1) is also known PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt and RAC-PK-alpha, which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and RAC subfamily and is expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven. AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase).

纯度:

>92% as determined by reduced SDS-PAGE.

Less than 1.0 EU per ug by the LAL method.

Accession #:

AAH00479

您可能感兴趣的产品

Influenza B Strain B/Hong Kong 5/72 Antigen

货号：11-576

TMIGD2 Recombinant Protein

货号：RF16120-01

TIM3 Recombinant Protein

货号：RF16100-01

B7-H3 Recombinant Protein