| 货号:BVT-0465-M001 | 规格:1 mg | 目录价:¥1020 |
| 货号:BVT-0465-M005 | 规格:5 mg | 目录价:¥3420 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Alternariol
别名:
AOH; NSC 638263; 3,4',5-Trihydroxy-6'-methyldibenzo-alpha-pyrone
产品描述:
Mycotoxin. Phytotoxin. Shows cytotoxic, teratogenic, mutagenic and genotoxic properties by DNA intercalation. Induces several types of DNA damage, including oxidative DNA damage, single-stranded DNA breaks (SSB) and double-strand, through AOH-induced ROS production and interaction with DNA topoisomerase. Inhibits the activity of topoisomerase IIalpha in mammalian cells. Induces cell growth arrest in G2/M phase. GSK-3beta inhibitor (sub-µM IC50 values). Antiviral activity (herpes simplex). Hepatitis C NS3-4A protease inhibitor. Induces cytochrome P450 1A1 expression and apoptosis in mouse hepatoma cells.
宿主来源:
Isolated from Alternaria sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
258.2
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
641-38-3
分子式:
C14H10O5
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