AMPK alpha 2 antibody-多抗-深圳欣博盛生物科技有限公司

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AMPK alpha 2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX23760

规格：50μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

AMPK alpha 2 antibody

别名:

AMPK , AMPK2 , AMPKa2 , PRKAA , PRKAA2 , protein kinase AMPactivated catalytic subunit alpha 2 , AMPK alpha 2 , protein kinase AMP-activated catalytic subunit alpha 2

反应种属:

Bovine, Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

IP, WB

靶标/特异性:

The epitope recognized is in the region between aa 350 and 400 of AMPK alpha-2.

同种型:

IgG

免疫原:

Synthetic peptide representing a portion of the protein encoded within exon 7.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

Tris-Citrate/Phosphate, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

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