Artemis antibody-多抗-深圳欣博盛生物科技有限公司

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Artemis antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX23834

规格：100μg

目录价：￥9200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Artemis antibody

别名:

DNA cross-link repair 1C , A-SCID , DCLREC1C , RS-SCID , SCIDA , SNM1C

反应种属:

Human

宿主来源:

Goat

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express artemis, such as the cell line CJ (see figure) and in an hTERT line (not shown).

同种型:

IgG

免疫原:

Synthetic peptide corresponding an internal region of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

1.2 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.

生产商:

GeneTex

功能与背景:

Human Artemis, a new identified 78.4 KD, novel DNA double-strand break repair/v(d)j recombination protein. This gene is located at human chromosome 10. Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.

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