| 货号:CDX-A0802-M500 | 规格:500 mg | 目录价:¥询价 |
| 货号:CDX-A0802-G001 | 规格:1 g | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Anastrozole
别名:
Anastrol; ICI-D 1033; ZD 1033; alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
产品描述:
Anastrozole is a highly potent, non-steroidal aromatase inhibitor that selectively inhibits the aromatase enzyme (CYP19A1) responsible for converting androgens to estrogens. With an IC50 in the low nanomolar range (typically ~15 nM), it effectively suppresses estrogen synthesis, making it a key compound in hormone-related cancer research. It is selective for aromatase/CYP19A1 over the cytochrome P450 (CYP) isoforms CYP1A2, CYP2A6, CYP2C9, CYP2D6, and CYP3A. Anastrozole is widely used in studies of estrogen receptor-positive (ER+) breast cancer, endocrine resistance and hormone regulation. It is a standard reference compound in preclinical drug screening and mechanistic studies targeting estrogen biosynthesis. Compound can be used as analytical reference material in relation to doping analytics.
宿主来源:
Synthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
293.37
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
120511-73-1
分子式:
C17H19N5
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