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折扣/货期| 货号：AG-CN2-0087-M001 | 规格：1 mg | 目录价：￥720 |
| 货号：AG-CN2-0087-M005 | 规格：5 mg | 目录价：￥2880 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Apicidin
别名:
cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl]; OSI-2040
产品描述:
Antiprotozoal [1]. Potent inhibitor of histone deacetylase (HDAC) [1,2]. Inhibits proliferation [2,3]. Induces cell cycle arrest at the G1 phase [2]. Induces hyperacetylation of histone H4 [5]. Apoptosis inducer [4,8,9]. Potent anti-angiogenic compound [5-7]. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines [3]. Autophagy inducer in oral squamous cell carcinoma (OSCC) cells [8]. Promotes either self-renewal or differentiation of embryonic stem cells [10].
宿主来源:
Isolated from fungus Fusarium sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
623.8
产品形式:
solid
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Stock solutions are stable for at least 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC, TLC)
CAS号:
183506-66-3
分子式:
C34H49N5O6
溶解度:
Soluble in ethanol or DMSO.
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