Apo A1 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Apo A1 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-031

规格：0.05 mg

目录价：￥9477

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Apo A1 Recombinant Protein

别名:

Apolipoprotein A-I, APOA1, MGC117399

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

ApoA1 is also known as apolipoprotein A-I, ApoA-I , and is the major protein component of high density lipoprotein (HDL) in plasma. It has a specific role in lipid metabolism. Chylomicrons secreted from the intestinal enterocyte also contain ApoA1 but it is quickly transferred to HDL in the bloodstream. The protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I was also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. In addition, it has been shown that ApoA1 is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.

纯度:

>95% as determined by SDS-PAGE.

生物活性:

Immobilized Human ApoAI at 10μg/mL (100μl/well) can bind biotinylated human SCARB1. The EC50 of biotinylated human SCARB1 is 10-100 ng/mL.

Accession #:

NP_000030.1

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