Arzanol-其他小分子化合物-深圳欣博盛生物科技有限公司

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Arzanol

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0500-M001

规格：1 mg

目录价：￥1680

产品详情

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产品名称:

Arzanol

别名:

Homoarenol; 3-[[3-Acetyl-2,4,6-trihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]methyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one

产品描述:

Brain glycogen phosphorylase (bGP) agonist. Arzanol directly interacts with bGP, competing for the same allosteric binding site on bGP like AMP (but with higher affinity), inducing similar conformational changes and promoting the transition to the active form, consequently leading to increased bGP enzyme activity. GPs are key enzymes in glycogen metabolism, promoting the rate-limiting step of its mobilization. In brain, glycogen acts as an emergency glucose storage to protect neurons against hypoglycemia and hypoxic stress, being critical for high cognitive processes such as learning and memory consolidation. Reduced glycogen breakdown is associated with impaired cognitive functions and neuro-degeneration. Activation of glycogen breakdown might be a new therapeutic strategy. Anti-inflammatory compound. Potent dual inhibitor of pro-inflammatory transcription factors and inflammatory enzymes. Inhibitor of NFkappaB activation. Potent inhibitor of inducible microsomal prostaglandin E2 synthase-1 (mPGES-1), the terminal synthase responsible for the synthesis of the pro-tumorigenic prostaglandin E2 (PGE2). Antioxidant. 5-Lipoxygenase (5-LO) inhibitor. Antibacterial compound. HIV-1 replication inhibitor.

宿主来源:

Isolated from Helichrysum italicum.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

402.4

产品形式:

solid

产地:

瑞士