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折扣/货期| 货号：10-169 | 规格：0.1 mg | 目录价：￥9038.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Basiliximab (IL2RA/CD25) - Research Grade Biosimilar
别名:
CHI621
同种型:
IgG1-kappa
克隆性:
Recombinant Monoclonal
纯化方式:
>95%
偶联:
Unconjugated
产品浓度:
batch dependent
表达系统:
CHO cells
保存温度:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.
运输温度:
Blue Ice
存储溶液:
PBS buffer pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent,specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes.It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.Basiliximab binds with high-affinity to the alpha-subunit (CD25) of the high-affinity IL-2 receptor.This inhibits IL-2 binding, which inhibits T-cell activation and prevents the body from mounting an immune response against the foreign kidney.
上一个:Alg-991 (Urushiol) - Research Grade Biosimilar
下一个:Bavituximab (Phosphatidylserine) - Research Grade Biosimilar
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