| 货号:40-496-0.002 mg | 规格:0.002 mg | 目录价:¥3783 |
| 货号:40-496-0.01 mg | 规格:0.01 mg | 目录价:¥5674.5 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BDNF Recombinant Protein
别名:
ANON2, BULN2, Brain-derived neurotrophic factor, Abrineurin, BDNF
表达系统:
E. coli
保存温度:
The lyophilized BDNF recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted BDNF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing BDNF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
生物活性:
Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.
Accession #:
NP_001137277.1
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