Biotinylated PSGL-1 / CD162 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Biotinylated PSGL-1 / CD162 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：11-116

规格：0.025 mg

目录价：￥10126

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Biotinylated PSGL-1 / CD162 Recombinant Protein

别名:

PSGL1,CD162,SELPLG,Selectin P ligand

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

P-selectin glycoprotein ligand 1 (PSGL-1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL-1 is disulfide-linked homodimer which is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 / SELPLG interacts with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for P-selectin/SELP binding. PSGL-1 can interact with SNX20, MSN and SYK. PSGL-1 / SELPLG mediate the activation of SYK by SELPLG.

纯度:

>90% as determined by SDS-PAGE.

Accession #:

NP_002997.2

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