深圳欣博盛生物科技有限公司 a1

Borrelidin
货号:BVT-0098-C500 规格:500 ug 目录价:¥960
货号:BVT-0098-M001 规格:1 mg 目录价:¥1440
货号:BVT-0098-M005 规格:5 mg 目录价:¥4800
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Borrelidin
别名:
Treponemycin; U 78548; C2989
产品描述:
Macrolide antibiotic. Bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Cyclin-dependent kinase (CDK) inhibitor. Antiviral. Potent antimalarial agent (IC50 = 0.97 nM). Inhibitor of potato scab disease.
宿主来源:
Isolated from Streptomyces sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
489.6
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
7184-60-3
分子式:
C28H43NO6
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