Carbonic Anhydrase 2 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Carbonic Anhydrase 2 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-072

规格：0.1 mg

目录价：￥8125.65

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Carbonic Anhydrase 2 Recombinant Protein

别名:

CA2, CA-II, CAII, Car2

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

20 mM Tris, pH 8.0, with 150 mM NaCl, 1 mM DTT.

产地:

美国

生产商:

Prosci

功能与背景:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. They are, therefore, classified as metalloenzymes. There are at least five distinct CA families (α, β, γ, δ and ε). These families have no significant amino acid sequence similarity and in most cases are thought to be an example of convergent evolution. The α-CAs are found in humans. Carbonic anhydrase II (CA2) is also known as Carbonate dehydratase II, Carbonic anhydrase C, is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.

纯度:

>95% as determined by SDS-PAGE.

生物活性:

Measured by its esterase activity for digestion of 4Nitrophenyl Acetate(4NPA). The specific activity is > 150 pmoles/min/μg.

Accession #:

NP_000058.1

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