| 货号:CDX-C0697-M005 | 规格:5 mg | 目录价:¥896 |
| 货号:CDX-C0697-M025 | 规格:25 mg | 目录价:¥3556 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Cardamonin
别名:
(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one; Alpinetin chalcone; (E)-2',4'-Dihydroxy-6'-methoxy-chalcone
产品描述:
Cardamonin is a calchone from Aplinia species (zingiberaceous plant species) with anti-cancer and anti-inflammatory, anti-nociceptive activity. Cardamonin suppresses NF-kappa nuclear translocation and Ik-Ba phosphorylation. It has been shown to suppress nitric oxide and prostaglandin E2 synthesis, to suppress cyclooxygenase-2 expression, and to inhibit NF-kappa signaling. It induces apoptosis in cancer cells, suppresses melanogenesis by inhibition of Wnt/beta-catenin signaling and ameliorates insulin resistance. It has been shown to induce autophagy and an antiproliferative effect through JNK activation. It is an hTRPA1 antagonist and shows also anti-parasitic activity. Also shown inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.
宿主来源:
Plant
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
270.28
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at RT.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
19309-14-9
分子式:
C16H14O4
溶解度:
Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (1mg/ml).
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